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Planetary-scale metagenomic analysis reveals CRISPR targeting dynamics across ecosystems - Nature

Reported by Nature.com | October 29, 2026, 6:00 pm

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Screening millions of CRISPR spacers across globally distributed metagenomes reveals unexpected dynamics of phage–host interactions, including many cases where phage genomes seem to repeatedly enter non-host cells.

Source data of CRISPR repeat database, repeat identification and dereplication
To build a global database of CRISPR repeat sequences, CRISPR repeats were searched for across 383,318 bacterial and ar…

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